CATH Domain 6fmcA00

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.60	Sandwich
	2.60.120	Jelly Rolls
	2.60.120.260	Galactose-binding domain-like

Domain Context

CATH Clusters

Superfamily	Galactose-binding domain-like
Functional Family	Coagulation factor VIII

Enzyme Information

UniProtKB Entries (1)

NRP1_HUMAN

Homo sapiens

Neuropilin-1

PDB Structure

PDB	6FMC
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Small Molecule Neuropilin-1 Antagonists Combine Antiangiogenic and Antitumor Activity with Immune Modulation through Reduction of Transforming Growth Factor Beta (TGF beta ) Production in Regulatory T-Cells. Powell, J., Mota, F., Steadman, D., Soudy, C., Miyauchi, J.T., Crosby, S., Jarvis, A., Reisinger, T., Winfield, N., Evans, G., Finniear, A., Yelland, T., Chou, Y.T., Chan, A.W.E., O'Leary, A., Cheng, L., Liu, D., Fotinou, C., Milagre, C., Martin, J.F., Jia, H., Frankel, P., Djordjevic, S., Tsirka, S.E., Zachary, I.C., Selwood, D.L. J. Med. Chem.