CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.60 | Sandwich |
|
2.60.40 | Immunoglobulin-like |
|
2.60.40.10 | Immunoglobulins |
Domain Context
CATH Clusters
| Superfamily | Immunoglobulins |
| Functional Family | Immunoglobulin heavy constant gamma 1 |
Enzyme Information
UniProtKB Entries (1)
| O75015 |
FCG3B_HUMAN
Homo sapiens
Low affinity immunoglobulin gamma Fc region receptor III-B
|
PDB Structure
| PDB | 6EAQ |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
A single amino acid distorts the Fc gamma receptor IIIb/CD16b structure upon binding immunoglobulin G1 and reduces affinity relative to CD16a.
J. Biol. Chem.
|