CATH Domain 6ciyA01

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.20	Up-down Bundle
	1.20.920	Histone Acetyltransferase; Chain A
	1.20.920.10	Bromodomain-like

Domain Context

CATH Clusters

Superfamily	Bromodomain-like
Functional Family	Bromodomain-containing protein 4

Enzyme Information

UniProtKB Entries (1)

BRD4_HUMAN

Homo sapiens

Bromodomain-containing protein 4

PDB Structure

PDB	6CIY
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structural and Atropisomeric Factors Governing the Selectivity of Pyrimido-benzodiazipinones as Inhibitors of Kinases and Bromodomains. Wang, J., Erazo, T., Ferguson, F.M., Buckley, D.L., Gomez, N., Munoz-Guardiola, P., Dieguez-Martinez, N., Deng, X., Hao, M., Massefski, W., Fedorov, O., Offei-Addo, N.K., Park, P.M., Dai, L., DiBona, A., Becht, K., Kim, N.D., McKeown, M.R., Roberts, J.M., Zhang, J., Sim, T., Alessi, D.R., Bradner, J.E., Lizcano, J.M., Blacklow, S.C., Qi, J., Xu, X., Gray, N.S. ACS Chem. Biol.