CATH Domain 6bteA01

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.150	DNA polymerase; domain 1
	1.10.150.110	DNA polymerase beta, N-terminal domain-like

Domain Context

CATH Clusters

Superfamily	DNA polymerase beta, N-terminal domain-like
Functional Family	DNA polymerase beta

Enzyme Information

2.7.7.7	DNA-directed DNA polymerase. based on mapping to UniProt P06746 Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). -!- Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. -!- Cannot initiate a chain de novo. -!- Requires a primer which may be DNA or RNA. -!- See also EC 2.7.7.49.
4.2.99.-	Other carbon-oxygen lyases. based on mapping to UniProt P06746

UniProtKB Entries (1)

DPOLB_HUMAN

Homo sapiens

DNA polymerase beta

PDB Structure

PDB	6BTE
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	I260Q DNA polymerase beta highlights precatalytic conformational rearrangements critical for fidelity. Liptak, C., Mahmoud, M.M., Eckenroth, B.E., Moreno, M.V., East, K., Alnajjar, K.S., Huang, J., Towle-Weicksel, J.B., Doublie, S., Loria, J.P., Sweasy, J.B. Nucleic Acids Res.