1 keywords

CATH Domain 6brbA00

CATH Classification

Level CATH Code Description
Class 2 Mainly Beta
Architecture 2.60 Sandwich
Topology 2.60.120 Jelly Rolls
Homologous Superfamily 2.60.120.40  

Domain Context

CATH Clusters

Superfamily 2.60.120.40
Functional Family CD40 ligand

Enzyme Information

UniProtKB Entries (1)

P24821
TENA_HUMAN
Homo sapiens
Tenascin

PDB Structure

PDB 6BRB
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
A CD40L-targeting protein reduces autoantibodies and improves disease activity in patients with autoimmunity.
Karnell, J.L., Albulescu, M., Drabic, S., Wang, L., Moate, R., Baca, M., Oganesyan, V., Gunsior, M., Thisted, T., Yan, L., Li, J., Xiong, X., Eck, S.C., de Los Reyes, M., Yusuf, I., Streicher, K., Muller-Ladner, U., Howe, D., Ettinger, R., Herbst, R., Drappa, J.
Sci Transl Med