CATH Classification
Level | CATH Code | Description |
---|---|---|
1 | Mainly Alpha | |
1.10 | Orthogonal Bundle | |
1.10.565 | Retinoid X Receptor | |
1.10.565.10 | Retinoid X Receptor |
Domain Context
CATH Clusters
Superfamily | Retinoid X Receptor |
Functional Family | Nuclear orphan receptor ROR-beta |
Enzyme Information
UniProtKB Entries (1)
P51449 |
RORG_HUMAN
Homo sapiens
Nuclear receptor ROR-gamma
|
PDB Structure
PDB | 6BR3 |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Discovery of [ cis-3-({(5 R)-5-[(7-Fluoro-1,1-dimethyl-2,3-dihydro-1 H-inden-5-yl)carbamoyl]-2-methoxy-7,8-dihydro-1,6-naphthyridin-6(5 H)-yl}carbonyl)cyclobutyl]acetic Acid (TAK-828F) as a Potent, Selective, and Orally Available Novel Retinoic Acid Receptor-Related Orphan Receptor gamma t Inverse Agonist.
J. Med. Chem.
|