CATH Domain 6bqdB00

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.20	Up-down Bundle
	1.20.920	Histone Acetyltransferase; Chain A
	1.20.920.10	Bromodomain-like

Domain Context

CATH Clusters

Superfamily	Bromodomain-like
Functional Family	Transcription initiation factor TFIID subunit

Enzyme Information

2.7.11.1	Non-specific serine/threonine protein kinase. based on mapping to UniProt P21675 ATP + a protein = ADP + a phosphoprotein. -!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.
2.3.1.48	Histone acetyltransferase. based on mapping to UniProt P21675 Acetyl-CoA + [protein]-L-lysine = CoA + [protein]-N(6)-acetyl-L-lysine. -!- A group of enzymes acetylating histones. -!- Several of the enzymes can also acetylate lysines in other proteins.

UniProtKB Entries (1)

TAF1_HUMAN

Homo sapiens

Transcription initiation factor TFIID subunit 1

PDB Structure

PDB	6BQD
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Water molecules in protein-ligand interfaces. Evaluation of software tools and SAR comparison. Nittinger, E., Gibbons, P., Eigenbrot, C., Davies, D.R., Maurer, B., Yu, C.L., Kiefer, J.R., Kuglstatter, A., Murray, J., Ortwine, D.F., Tang, Y., Tsui, V. J. Comput. Aided Mol. Des.