CATH Classification

Domain Context

CATH Clusters

Superfamily 1.20.58.1480
Functional Family Cereblon, isoform CRA_c

Enzyme Information

UniProtKB Entries (1)

O60885
BRD4_HUMAN
Homo sapiens
Bromodomain-containing protein 4

PDB Structure

PDB 6BN7
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Plasticity in binding confers selectivity in ligand-induced protein degradation.
Nowak, R.P., DeAngelo, S.L., Buckley, D., He, Z., Donovan, K.A., An, J., Safaee, N., Jedrychowski, M.P., Ponthier, C.M., Ishoey, M., Zhang, T., Mancias, J.D., Gray, N.S., Bradner, J.E., Fischer, E.S.
Nat. Chem. Biol.