CATH Domain 5yi5O00

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.20	Up-down Bundle
	1.20.1260	Ferritin
	1.20.1260.10	Ferritin, core subunit, four-helix bundle

Domain Context

CATH Clusters

Superfamily	1.20.1260.10
Functional Family	Ferritin heavy chain

Enzyme Information

1.16.3.1

Ferroxidase.

based on mapping to UniProt P02794

4 Fe(2+) + 4 H(+) + O(2) = 4 Fe(3+) + 2 H(2)O.

UniProtKB Entries (1)

FRIH_HUMAN

Homo sapiens

Ferritin heavy chain

PDB Structure

PDB	5YI5
External Links	PDBSum Proteopedia
Method	ELECTRON MICROSCOPY
Organism
Primary Citation	Four-fold Channel-Nicked Human Ferritin Nanocages for Active Drug Loading and pH-Responsive Drug Release Ahn, B., Lee, S.G., Yoon, H.R., Lee, J.M., Oh, H.J., Kim, H.M., Jung, Y. Angew. Chem. Int. Ed. Engl.