CATH Classification

Domain Context

CATH Clusters

Superfamily 1.10.10.2230
Functional Family DNA (cytosine-5)-methyltransferase

Enzyme Information

2.1.1.37
DNA (cytosine-5-)-methyltransferase.
based on mapping to UniProt P26358
S-adenosyl-L-methionine + DNA = S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine.
-!- See the REBASE database for a complete list of these enzymes: http://rebase.neb.com/rebase/ -!- Formerly EC 2.1.1.73.

UniProtKB Entries (1)

P0CG47
UBB_HUMAN
Homo sapiens
Polyubiquitin-B

PDB Structure

PDB 5YDR
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural and mechanistic insights into UHRF1-mediated DNMT1 activation in the maintenance DNA methylation.
Li, T., Wang, L., Du, Y., Xie, S., Yang, X., Lian, F., Zhou, Z., Qian, C.
Nucleic Acids Res.