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CATH Classification

Domain Context

CATH Clusters

Superfamily Nucleic acid-binding proteins
Functional Family Exosome complex exonuclease DIS3

Enzyme Information

3.1.26.-
Endoribonucleases producing 5'-phosphomonoesters.
based on mapping to UniProt Q08162
3.1.13.-
Exoribonucleases producing 5'-phosphomonoesters.
based on mapping to UniProt Q08162

UniProtKB Entries (1)

P53256
RRP46_YEAST
Saccharomyces cerevisiae S288C
Exosome complex component RRP46

PDB Structure

PDB 5VZJ
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure and reconstitution of yeast Mpp6-nuclear exosome complexes reveals that Mpp6 stimulates RNA decay and recruits the Mtr4 helicase.
Wasmuth, E.V., Zinder, J.C., Zattas, D., Das, M., Lima, C.D.
Elife
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