CATH Domain 5v59A01

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.930	BirA Bifunctional Protein; domain 2
	3.30.930.10	Bira Bifunctional Protein; Domain 2

Domain Context

CATH Clusters

Superfamily	Bira Bifunctional Protein; Domain 2
Functional Family	Alanine--tRNA ligase, cytoplasmic

Enzyme Information

6.1.1.7

Alanine--tRNA ligase.

based on mapping to UniProt P49588

ATP + L-alanine + tRNA(Ala) = AMP + diphosphate + L-alanyl-tRNA(Ala).

UniProtKB Entries (1)

SYAC_HUMAN

Homo sapiens

Alanine--tRNA ligase, cytoplasmic

PDB Structure

PDB	5V59
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Double mimicry evades tRNA synthetase editing by toxic vegetable-sourced non-proteinogenic amino acid. Song, Y., Zhou, H., Vo, M.N., Shi, Y., Nawaz, M.H., Vargas-Rodriguez, O., Diedrich, J.K., Yates, J.R., Kishi, S., Musier-Forsyth, K., Schimmel, P. Nat Commun