CATH Classification

Domain Context

CATH Clusters

Superfamily 1.20.1250.10
Functional Family Interleukin-2

Enzyme Information

UniProtKB Entries (1)

P60568
IL2_HUMAN
Homo sapiens
Interleukin-2

PDB Structure

PDB 5UTZ
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
A human anti-IL-2 antibody that potentiates regulatory T cells by a structure-based mechanism.
Trotta, E., Bessette, P.H., Silveria, S.L., Ely, L.K., Jude, K.M., Le, D.T., Holst, C.R., Coyle, A., Potempa, M., Lanier, L.L., Garcia, K.C., Crellin, N.K., Rondon, I.J., Bluestone, J.A.
Nat. Med.