1 keywords

CATH Domain 5uhiB00

CATH Classification

Level CATH Code Description
Class 1 Mainly Alpha
Architecture 1.10 Orthogonal Bundle
Topology 1.10.565 Retinoid X Receptor
Homologous Superfamily 1.10.565.10 Retinoid X Receptor

Domain Context

CATH Clusters

Superfamily Retinoid X Receptor
Functional Family Nuclear orphan receptor ROR-beta

Enzyme Information

UniProtKB Entries (1)

P51449
RORG_HUMAN
Homo sapiens
Nuclear receptor ROR-gamma

PDB Structure

PDB 5UHI
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Identification and structure activity relationships of quinoline tertiary alcohol modulators of ROR gamma t.
Kummer, D.A., Cummings, M.D., Abad, M., Barbay, J., Castro, G., Wolin, R., Kreutter, K.D., Maharoof, U., Milligan, C., Nishimura, R., Pierce, J., Schalk-Hihi, C., Spurlino, J., Urbanski, M., Venkatesan, H., Wang, A., Woods, C., Xue, X., Edwards, J.P., Fourie, A.M., Leonard, K.
Bioorg. Med. Chem. Lett.