CATH Domain 5uc4A00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.565	Heat Shock Protein 90
	3.30.565.10	Histidine kinase-like ATPase, C-terminal domain

Domain Context

CATH Clusters

Superfamily	Histidine kinase-like ATPase, C-terminal domain
Functional Family	Heat shock protein HSP 90-beta

Enzyme Information

UniProtKB Entries (1)

HS90B_HUMAN

Homo sapiens

Heat shock protein HSP 90-beta

PDB Structure

PDB	5UC4
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structure-guided design of an Hsp90 beta N-terminal isoform-selective inhibitor. Khandelwal, A., Kent, C.N., Balch, M., Peng, S., Mishra, S.J., Deng, J., Day, V.W., Liu, W., Subramanian, C., Cohen, M., Holzbeierlein, J.M., Matts, R., Blagg, B.S.J. Nat Commun