CATH Classification

Domain Context

CATH Clusters

Superfamily PAS domain
Functional Family Nuclear receptor coactivator

Enzyme Information

2.3.1.48
Histone acetyltransferase.
based on mapping to UniProt P70365
Acetyl-CoA + [protein]-L-lysine = CoA + [protein]-N(6)-acetyl-L-lysine.
-!- A group of enzymes acetylating histones. -!- Several of the enzymes can also acetylate lysines in other proteins.

UniProtKB Entries (2)

P70365
NCOA1_MOUSE
Mus musculus
Nuclear receptor coactivator 1
P42226
STAT6_HUMAN
Homo sapiens
Signal transducer and activator of transcription 6

PDB Structure

PDB 5NWX
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Insight into the molecular recognition mechanism of the coactivator NCoA1 by STAT6.
Russo, L., Giller, K., Pfitzner, E., Griesinger, C., Becker, S.
Sci Rep