CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.760 | RNA Cap, Translation Initiation Factor Eif4e |
|
3.30.760.10 | RNA Cap, Translation Initiation Factor Eif4e |
Domain Context
CATH Clusters
| Superfamily | RNA Cap, Translation Initiation Factor Eif4e |
| Functional Family | Eukaryotic translation initiation factor 4E type 2 isoformX2 |
Enzyme Information
UniProtKB Entries (1)
| O60573 |
IF4E2_HUMAN
Homo sapiens
Eukaryotic translation initiation factor 4E type 2
|
PDB Structure
| PDB | 5NVN |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
GIGYF1/2 proteins use auxiliary sequences to selectively bind to 4EHP and repress target mRNA expression.
Genes Dev.
|