CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.60 | Sandwich |
|
2.60.40 | Immunoglobulin-like |
|
2.60.40.10 | Immunoglobulins |
Domain Context
CATH Clusters
| Superfamily | Immunoglobulins |
| Functional Family | Immunoglobulin heavy constant gamma 1 |
Enzyme Information
UniProtKB Entries (1)
| P01854 |
IGHE_HUMAN
Homo sapiens
Immunoglobulin heavy constant epsilon
|
PDB Structure
| PDB | 5NQW |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Trapping IgE in a closed conformation by mimicking CD23 binding prevents and disrupts Fc epsilon RI interaction.
Nat Commun
|
