CATH Classification

Domain Context

CATH Clusters

Superfamily Trypsin-like serine proteases
Functional Family Complement factor D

Enzyme Information

UniProtKB Entries (0)

PDB Structure

PDB 5NAT
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Discovery of Highly Potent and Selective Small-Molecule Reversible Factor D Inhibitors Demonstrating Alternative Complement Pathway Inhibition in Vivo.
Lorthiois, E., Anderson, K., Vulpetti, A., Rogel, O., Cumin, F., Ostermann, N., Steinbacher, S., Mac Sweeney, A., Delgado, O., Liao, S.M., Randl, S., Rudisser, S., Dussauge, S., Fettis, K., Kieffer, L., de Erkenez, A., Yang, L., Hartwieg, C., Argikar, U.A., La Bonte, L.R., Newton, R., Kansara, V., Flohr, S., Hommel, U., Jaffee, B., Maibaum, J.
J.Med.Chem.
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