×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

CATH Classification

Domain Context

CATH Clusters

Superfamily Protein tyrosine phosphatase superfamily
Functional Family protein tyrosine phosphatase type IVA 1

Enzyme Information

3.1.3.48
Protein-tyrosine-phosphatase.
based on mapping to UniProt Q63739
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.
-!- Dephosphorylates O-phosphotyrosine groups in phosphoproteins, such as the products of EC 2.7.10.2.

UniProtKB Entries (1)

Q63739
TP4A1_MOUSE
Mus musculus
Protein tyrosine phosphatase type IVA 1

PDB Structure

PDB 5MMZ
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural Basis of the Oncogenic Interaction of Phosphatase PRL-1 with the Magnesium Transporter CNNM2.
Gimenez-Mascarell, P., Oyenarte, I., Hardy, S., Breiderhoff, T., Stuiver, M., Kostantin, E., Diercks, T., Pey, A.L., Ereno-Orbea, J., Martinez-Chantar, M.L., Khalaf-Nazzal, R., Claverie-Martin, F., Muller, D., Tremblay, M.L., Martinez-Cruz, L.A.
J. Biol. Chem.
CATH-Gene3D is a Global Biodata Core Resource Learn more...