CATH Classification

Domain Context

CATH Clusters

Superfamily von Hippel-Lindau disease tumour suppressor, beta domain
Functional Family von Hippel-Lindau disease tumor suppressor

Enzyme Information

UniProtKB Entries (1)

Q15370
ELOB_HUMAN
Homo sapiens
Elongin-B

PDB Structure

PDB 5LLI
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Potent and selective chemical probe of hypoxic signalling downstream of HIF-alpha hydroxylation via VHL inhibition.
Frost, J., Galdeano, C., Soares, P., Gadd, M.S., Grzes, K.M., Ellis, L., Epemolu, O., Shimamura, S., Bantscheff, M., Grandi, P., Read, K.D., Cantrell, D.A., Rocha, S., Ciulli, A.
Nat Commun