CATH Domain 5liaA03

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.720	Alkaline Phosphatase, subunit A
	3.40.720.10	Alkaline Phosphatase, subunit A

Superfamily	Alkaline Phosphatase, subunit A
Functional Family	Ectonucleotide pyrophosphatase/phosphodiesterase family member 2

3.1.4.39

Alkylglycerophosphoethanolamine phosphodiesterase.

based on mapping to UniProt Q9R1E6

1-alkyl-sn-glycero-3-phosphoethanolamine + H(2)O = 1-alkyl-sn-glycerol 3-phosphate + ethanolamine.

-!- Also acts on acyl and choline analogs.

ENPP2_MOUSE

Mus musculus

Ectonucleotide pyrophosphatase/phosphodiesterase family member 2

PDB	5LIA
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Discovery of potent inhibitors of the lysophospholipase autotaxin. Shah, P., Cheasty, A., Foxton, C., Raynham, T., Farooq, M., Gutierrez, I.F., Lejeune, A., Pritchard, M., Turnbull, A., Pang, L., Owen, P., Boyd, S., Stowell, A., Jordan, A., Hamilton, N.M., Hitchin, J.R., Stockley, M., MacDonald, E., Quesada, M.J., Trivier, E., Skeete, J., Ovaa, H., Moolenaar, W.H., Ryder, H. Bioorg. Med. Chem. Lett.