CATH Domain 5kaeA04

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.1010	Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 4
	3.30.1010.10	Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 4

Superfamily	Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 4
Functional Family	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma

PDB	5KAE
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Discovery and in vivo evaluation of the potent and selective PI3K-delta inhibitors AM-0687 and AM-1430 Gonzalez-Lopez de Turiso, F., Hao, X., Shin, Y., Bui, M., Campuzano, I., Cardozo, M., Dunn, M.C., Duquette, J., Fisher, B., Foti, R.S., Henne, K., He, X., Hu, Y.-L., Kelly, R.C., Johnson, M.G., Lucas, B.S., McCarter, J., McGee, L.R., Medina, J.C., Metz, D., San Miguel, T., Mohn, D., Tran, T., Vissinga, C., Wannberg, S., Whittington, D.A., Whoriskey, J., Yu, G., Zalameda, L., Zhang, X., Cushing, T.D. To Be Published