CATH Domain 5jnmA02

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CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.1040	N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2
	1.10.1040.10	N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2

Domain Context

CATH Clusters

Superfamily	N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2
Functional Family	Mannitol-1-phosphate 5-dehydrogenase

Enzyme Information

1.1.1.17

Mannitol-1-phosphate 5-dehydrogenase.

based on mapping to UniProt A7X522

D-mannitol 1-phosphate + NAD(+) = D-fructose 6-phosphate + NADH.

UniProtKB Entries (1)

MTLD_STAA1

Staphylococcus aureus subsp. aureus Mu3

Mannitol-1-phosphate 5-dehydrogenase

PDB Structure

PDB	5JNM
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Targeting Mannitol Metabolism as an Alternative Antimicrobial Strategy Based on the Structure-Function Study of Mannitol-1-Phosphate Dehydrogenase in Staphylococcus aureus. Nguyen, T., Kim, T., Ta, H.M., Yeo, W.S., Choi, J., Mizar, P., Lee, S.S., Bae, T., Chaurasia, A.K., Kim, K.K. Mbio