CATH Domain 5igmA00

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.20	Up-down Bundle
	1.20.920	Histone Acetyltransferase; Chain A
	1.20.920.10	Bromodomain-like

Domain Context

CATH Clusters

Superfamily	Bromodomain-like
Functional Family	Putative bromodomain-containing protein 9

Enzyme Information

UniProtKB Entries (1)

BRD9_HUMAN

Homo sapiens

Bromodomain-containing protein 9

PDB Structure

PDB	5IGM
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Promiscuous targeting of bromodomains by bromosporine identifies BET proteins as master regulators of primary transcription response in leukemia. Picaud, S., Leonards, K., Lambert, J.P., Dovey, O., Wells, C., Fedorov, O., Monteiro, O., Fujisawa, T., Wang, C.Y., Lingard, H., Tallant, C., Nikbin, N., Guetzoyan, L., Ingham, R., Ley, S.V., Brennan, P., Muller, S., Samsonova, A., Gingras, A.C., Schwaller, J., Vassiliou, G., Knapp, S., Filippakopoulos, P. Sci Adv