CATH Domain 5iglA00

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.20	Up-down Bundle
	1.20.920	Histone Acetyltransferase; Chain A
	1.20.920.10	Bromodomain-like

Domain Context

CATH Clusters

Superfamily	Bromodomain-like
Functional Family	Transcription initiation factor TFIID subunit

Enzyme Information

UniProtKB Entries (1)

TAF1L_HUMAN

Homo sapiens

Transcription initiation factor TFIID subunit 1-like

PDB Structure

PDB	5IGL
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Promiscuous targeting of bromodomains by bromosporine identifies BET proteins as master regulators of primary transcription response in leukemia. Picaud, S., Leonards, K., Lambert, J.P., Dovey, O., Wells, C., Fedorov, O., Monteiro, O., Fujisawa, T., Wang, C.Y., Lingard, H., Tallant, C., Nikbin, N., Guetzoyan, L., Ingham, R., Ley, S.V., Brennan, P., Muller, S., Samsonova, A., Gingras, A.C., Schwaller, J., Vassiliou, G., Knapp, S., Filippakopoulos, P. Sci Adv