CATH Classification

Domain Context

CATH Clusters

Superfamily TAZ domain
Functional Family E1A binding protein p300

Enzyme Information

2.3.1.48
Histone acetyltransferase.
based on mapping to UniProt P45481
Acetyl-CoA + [protein]-L-lysine = CoA + [protein]-N(6)-acetyl-L-lysine.
-!- A group of enzymes acetylating histones. -!- Several of the enzymes can also acetylate lysines in other proteins.

UniProtKB Entries (2)

P45481
CBP_MOUSE
Mus musculus
CREB-binding protein
P04637
P53_HUMAN
Homo sapiens
Cellular tumor antigen p53

PDB Structure

PDB 5HP0
External Links
Method SOLUTION NMR
Organism
Primary Citation
Recognition of the disordered p53 transactivation domain by the transcriptional adapter zinc finger domains of CREB-binding protein.
Krois, A.S., Ferreon, J.C., Martinez-Yamout, M.A., Dyson, H.J., Wright, P.E.
Proc.Natl.Acad.Sci.USA