CATH Classification

Domain Context

CATH Clusters

Superfamily Helix hairpin bin
Functional Family Tubulin beta chain

Enzyme Information

UniProtKB Entries (4)

P63043
STMN4_RAT
Rattus norvegicus
Stathmin-4
E1BQ43
E1BQ43_CHICK
Gallus gallus
Uncharacterized protein
Q2XVP4
TBA1B_PIG
Sus scrofa
Tubulin alpha-1B chain
Q6B856
TBB2B_BOVIN
Bos taurus
Tubulin beta-2B chain

PDB Structure

PDB 5H7O
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
A Potent, Metabolically Stable Tubulin Inhibitor Targets the Colchicine Binding Site and Overcomes Taxane Resistance.
Arnst, K.E., Wang, Y., Hwang, D.J., Xue, Y., Costello, T., Hamilton, D., Chen, Q., Yang, J., Park, F., Dalton, J.T., Miller, D.D., Li, W.
Cancer Res.
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