CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.261 | Succinyl-CoA synthetase domains |
Domain Context
CATH Clusters
| Superfamily | Succinyl-CoA synthetase domains |
| Functional Family | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial |
Enzyme Information
| 6.2.1.4 |
Succinate--CoA ligase (GDP-forming).
based on mapping to UniProt O19069
GTP + succinate + CoA = GDP + phosphate + succinyl-CoA.
-!- Itaconate can act instead of succinate and ITP instead of GTP.
|
| 6.2.1.5 |
Succinate--CoA ligase (ADP-forming).
based on mapping to UniProt O19069
ATP + succinate + CoA = ADP + phosphate + succinyl-CoA.
|
UniProtKB Entries (1)
| O19069 |
SUCA_PIG
Sus scrofa
Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial
|
PDB Structure
| PDB | 5CAE |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structural basis for the binding of succinate to succinyl-CoA synthetase.
Acta Crystallogr D Struct Biol
|