CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.565 | Retinoid X Receptor |
|
1.10.565.10 | Retinoid X Receptor |
Domain Context
CATH Clusters
| Superfamily | Retinoid X Receptor |
| Functional Family | Nuclear orphan receptor ROR-beta |
Enzyme Information
UniProtKB Entries (1)
| P51449 |
RORG_HUMAN
Homo sapiens
Nuclear receptor ROR-gamma
|
PDB Structure
| PDB | 5AYG |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
SAR Exploration Guided by LE and Fsp(3): Discovery of a Selective and Orally Efficacious ROR gamma Inhibitor
Acs Med.Chem.Lett.
|