CATH Domain 5anlA02

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.1010	Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 4
	3.30.1010.10	Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 4

Domain Context

CATH Clusters

Superfamily	Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 4
Functional Family	Phosphatidylinositol 3-kinase catalytic subunit type 3

Enzyme Information

2.7.1.137

Phosphatidylinositol 3-kinase.

based on mapping to UniProt Q8NEB9

ATP + 1-phosphatidyl-1D-myo-inositol = ADP + 1-phosphatidyl-1D-myo- inositol 3-phosphate.

UniProtKB Entries (1)

PK3C3_HUMAN

Homo sapiens

Phosphatidylinositol 3-kinase catalytic subunit type 3

PDB Structure

PDB	5ANL
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Automated Harvesting and Processing of Protein Crystals Through Laser Photoablation. Zander, U., Hoffmann, G., Cornaciu, I., Marquette, J.-P., Papp, G., Landret, C., Seroul, G., Sinoir, J., Roewer, M., Felisaz, F., Rodriguez-Puente, S., Mariaule, V., Murphy, P., Mathieu, M., Cipriani, F., Marquez, J.A. Acta Crystallogr.,Sect.D