1 keywords

CATH Domain 5a7wA01

CATH Classification

Level CATH Code Description
Class 2 Mainly Beta
Architecture 2.60 Sandwich
Topology 2.60.120 Jelly Rolls
Homologous Superfamily 2.60.120.650 Cupin

Domain Context

CATH Clusters

Superfamily Cupin
Functional Family Lysine-specific demethylase 4A

Enzyme Information

1.14.11.-
With 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors.
based on mapping to UniProt O75164

UniProtKB Entries (1)

O75164
KDM4A_HUMAN
Homo sapiens
Lysine-specific demethylase 4A

PDB Structure

PDB 5A7W
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Docking and Linking of Fragments to Discover Jumonji Histone Demethylase Inhibitors.
Korczynska, M., Le, D.D., Younger, N., Gregori-Puigjane, E., Tumber, A., Krojer, T., Velupillai, S., Gileadi, C., Nowak, R.P., Iwasa, E., Pollock, S.B., Ortiz Torres, I., Oppermann, U., Shoichet, B.K., Fujimori, D.G.
J.Med.Chem.