1 keywords

CATH Domain 4xt2B01

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.30 2-Layer Sandwich
Topology 3.30.450 Beta-Lactamase
Homologous Superfamily 3.30.450.20 PAS domain

Domain Context

CATH Clusters

Superfamily PAS domain
Functional Family Aryl hydrocarbon receptor nuclear translocator 1

Enzyme Information

UniProtKB Entries (1)

Q99814
EPAS1_HUMAN
Homo sapiens
Endothelial PAS domain-containing protein 1

PDB Structure

PDB 4XT2
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Isoform-Selective and Stereoselective Inhibition of Hypoxia Inducible Factor-2.
Scheuermann, T.H., Stroud, D., Sleet, C.E., Bayeh, L., Shokri, C., Wang, H., Caldwell, C.G., Longgood, J., MacMillan, J.B., Bruick, R.K., Gardner, K.H., Tambar, U.K.
J.Med.Chem.