CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.1820 | alpha/beta hydrolase |
Domain Context
CATH Clusters
| Superfamily | alpha/beta hydrolase |
| Functional Family | Acetylcholinesterase |
Enzyme Information
| 3.1.1.8 |
Cholinesterase.
based on mapping to UniProt P06276
An acylcholine + H(2)O = choline + a carboxylate.
-!- Acts on a variety of choline esters and a few other compounds.
|
UniProtKB Entries (1)
| P06276 |
CHLE_HUMAN
Homo sapiens
Cholinesterase
|
PDB Structure
| PDB | 4TPK |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Discovery, biological evaluation, and crystal structure of a novel nanomolar selective butyrylcholinesterase inhibitor.
J.Med.Chem.
|