CATH Classification

Domain Context

CATH Clusters

Superfamily Protein tyrosine phosphatase superfamily
Functional Family Tyrosine-protein phosphatase non-receptor type

Enzyme Information

3.1.3.48
Protein-tyrosine-phosphatase.
based on mapping to UniProt P26045
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.
-!- Dephosphorylates O-phosphotyrosine groups in phosphoproteins, such as the products of EC 2.7.10.2.

UniProtKB Entries (1)

P42566
EPS15_HUMAN
Homo sapiens
Epidermal growth factor receptor substrate 15

PDB Structure

PDB 4S0G
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Substrate Specificity and Plasticity of FERM-Containing Protein Tyrosine Phosphatases
Chen, K.E., Li, M.Y., Chou, C.C., Ho, M.R., Chen, G.C., Meng, T.C., Wang, A.H.-J.
Structure