CATH Domain 4rchA02

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.420	Nucleotidyltransferase; domain 5
	3.30.420.40	ATPase, nucleotide binding domain

Superfamily	3.30.420.40
Functional Family	Phosphotransferase

2.7.1.2

Glucokinase.

based on mapping to UniProt P35557

ATP + D-glucose = ADP + D-glucose 6-phosphate.

-!- A group of enzymes found in invertebrates and microorganisms highly specific for glucose.

HXK4_HUMAN

Homo sapiens

Glucokinase

PDB	4RCH
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Discovery of 2-pyridylureas as glucokinase activators. Hinklin, R.J., Aicher, T.D., Anderson, D.A., Baer, B.R., Boyd, S.A., Condroski, K.R., DeWolf, W.E., Kraser, C.F., McVean, M., Rhodes, S.P., Sturgis, H.L., Voegtli, W.C., Williams, L., Houze, J.B. J.Med.Chem.