CATH Classification

Domain Context

CATH Clusters

Superfamily NAD(P)-binding Rossmann-like Domain
Functional Family D-amino-acid oxidase

Enzyme Information

1.4.3.3
D-amino-acid oxidase.
based on mapping to UniProt P14920
A D-amino acid + H(2)O + O(2) = a 2-oxo acid + NH(3) + H(2)O(2).
-!- Wide specificity for D-amino acids. -!- Also acts on glycine.

UniProtKB Entries (1)

P14920
OXDA_HUMAN
Homo sapiens
D-amino-acid oxidase

PDB Structure

PDB 4QFC
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Novel human D-amino acid oxidase inhibitors stabilize an active-site lid-open conformation.
Terry-Lorenzo, R.T., Chun, L.E., Brown, S.P., Heffernan, M.L., Fang, Q.K., Orsini, M.A., Pollegioni, L., Hardy, L.W., Spear, K.L., Large, T.H.
Biosci.Rep.