CATH Domain 4pmwB04

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CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.40	Beta Barrel
	2.40.50	OB fold (Dihydrolipoamide Acetyltransferase, E2P)
	2.40.50.140	Nucleic acid-binding proteins

Domain Context

CATH Clusters

Superfamily	Nucleic acid-binding proteins
Functional Family	DIS3-like exonuclease 2

Enzyme Information

3.1.13.-

Exoribonucleases producing 5'-phosphomonoesters.

based on mapping to UniProt Q8CI75

UniProtKB Entries (1)

DI3L2_MOUSE

Mus musculus

DIS3-like exonuclease 2

PDB Structure

PDB	4PMW
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Mechanism of Dis3l2 substrate recognition in the Lin28-let-7 pathway. Faehnle, C.R., Walleshauser, J., Joshua-Tor, L. Nature