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1 keywords

CATH Domain 4p75D01

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.30 2-Layer Sandwich
Topology 3.30.930 BirA Bifunctional Protein; domain 2
Homologous Superfamily 3.30.930.10 Bira Bifunctional Protein; Domain 2

Domain Context

CATH Clusters

Superfamily Bira Bifunctional Protein; Domain 2
Functional Family Phenylalanine--tRNA ligase alpha subunit

Enzyme Information

6.1.1.20
Phenylalanine--tRNA ligase.
based on mapping to UniProt Q9I0A3
ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + L-phenylalanyl- tRNA(Phe).

UniProtKB Entries (1)

Q9I0A3
SYFA_PSEAE
Pseudomonas aeruginosa PAO1
Phenylalanine--tRNA ligase alpha subunit

PDB Structure

PDB 4P75
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The role of a novel auxiliary pocket in bacterial phenylalanyl-tRNA synthetase druggability.
Abibi, A., Ferguson, A.D., Fleming, P.R., Gao, N., Hajec, L.I., Hu, J., Laganas, V.A., McKinney, D.C., McLeod, S.M., Prince, D.B., Shapiro, A.B., Buurman, E.T.
J.Biol.Chem.
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