CATH Classification
Level | CATH Code | Description |
---|---|---|
2 | Mainly Beta | |
2.40 | Beta Barrel | |
2.40.128 | Lipocalin | |
2.40.128.20 | Calycin beta-barrel core domain |
Domain Context
CATH Clusters
Superfamily | 2.40.128.20 |
Functional Family | Prostaglandin-H2 D-isomerase |
Enzyme Information
5.3.99.2 |
Prostaglandin-D synthase.
based on mapping to UniProt P41222
(5Z,13E,15S)-9-alpha,11-alpha-epidioxy-15-hydroxyprosta-5,13-dienoate = (5Z,13E,15S)-9-alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate.
-!- Brings about the opening of the epidioxy bridge.
|
UniProtKB Entries (1)
P41222 |
PTGDS_HUMAN
Homo sapiens
Prostaglandin-H2 D-isomerase
|
PDB Structure
PDB | 4OS8 |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
High-resolution structures of mutants of residues that affect access to the ligand-binding cavity of human lipocalin-type prostaglandin D synthase.
Acta Crystallogr.,Sect.D
|