CATH Classification

Domain Context

CATH Clusters

Superfamily Ankyrin repeat-containing domain
Functional Family 2-5A-dependent ribonuclease

Enzyme Information

3.1.26.-
Endoribonucleases producing 5'-phosphomonoesters.
based on mapping to UniProt Q05823

UniProtKB Entries (1)

Q05823
RN5A_HUMAN
Homo sapiens
2-5A-dependent ribonuclease

PDB Structure

PDB 4OAV
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure of human RNase L reveals the basis for regulated RNA decay in the IFN response.
Han, Y., Donovan, J., Rath, S., Whitney, G., Chitrakar, A., Korennykh, A.
Science