CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.62 | Nef Regulatory Factor |
|
3.30.62.10 | Nef Regulatory Factor |
Domain Context
CATH Clusters
| Superfamily | Nef Regulatory Factor |
| Functional Family |
Enzyme Information
UniProtKB Entries (2)
| P18484 |
AP2A2_RAT
Rattus norvegicus
AP-2 complex subunit alpha-2
|
| P04601 |
NEF_HV1H2
HIV-1 M:B_HXB2R
Protein Nef
|
PDB Structure
| PDB | 4NEE |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
How HIV-1 Nef hijacks the AP-2 clathrin adaptor to downregulate CD4.
Elife
|