CATH Domain 4l9mA02

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.840	Son of Sevenless (SoS) protein; Chain S, domain 2
	1.10.840.10	Ras guanine-nucleotide exchange factors catalytic domain

Domain Context

CATH Clusters

Superfamily	Ras guanine-nucleotide exchange factors catalytic domain
Functional Family	Ras guanyl-releasing protein 3 isoform 1

Enzyme Information

UniProtKB Entries (1)

GRP1_HUMAN

Homo sapiens

RAS guanyl-releasing protein 1

PDB Structure

PDB	4L9M
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structural analysis of autoinhibition in the Ras-specific exchange factor RasGRP1. Iwig, J.S., Vercoulen, Y., Das, R., Barros, T., Limnander, A., Che, Y., Pelton, J.G., Wemmer, D.E., Roose, J.P., Kuriyan, J. Elife