CATH Classification
Level | CATH Code | Description |
---|---|---|
1 | Mainly Alpha | |
1.10 | Orthogonal Bundle | |
1.10.287 | Helix Hairpins | |
1.10.287.1490 |
Domain Context
CATH Clusters
Superfamily | 1.10.287.1490 |
Functional Family | Putative phosphatidylinositol 3-kinase regulatory subunit alpha |
Enzyme Information
UniProtKB Entries (1)
P42336 |
PK3CA_HUMAN
Homo sapiens
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
|
PDB Structure
PDB | 4L1B |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Crystal Structures of PI3K alpha Complexed with PI103 and Its Derivatives: New Directions for Inhibitors Design.
ACS Med Chem Lett
|