CATH Domain 4kqeA01

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.930	BirA Bifunctional Protein; domain 2
	3.30.930.10	Bira Bifunctional Protein; Domain 2

Domain Context

CATH Clusters

Superfamily	Bira Bifunctional Protein; Domain 2
Functional Family	Glycyl-tRNA synthetase 1

Enzyme Information

2.7.7.-	Nucleotidyltransferases. based on mapping to UniProt P41250
6.1.1.14	Glycine--tRNA ligase. based on mapping to UniProt P41250 ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly).

UniProtKB Entries (1)

GARS_HUMAN

Homo sapiens

Glycine--tRNA ligase

PDB Structure

PDB	4KQE
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Large Conformational Changes of Insertion 3 in Human Glycyl-tRNA Synthetase (hGlyRS) during Catalysis Deng, X., Qin, X., Chen, L., Jia, Q., Zhang, Y., Zhang, Z., Lei, D., Ren, G., Zhou, Z., Wang, Z., Li, Q., Xie, W. J.Biol.Chem.