CATH Domain 4j19B01

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CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.10	Arc Repressor Mutant, subunit A
	1.10.10.60	Homeodomain-like

Domain Context

CATH Clusters

Superfamily	Homeodomain-like
Functional Family	Homeobox-containing protein 1 isoform X2

Enzyme Information

UniProtKB Entries (1)

HMBX1_HUMAN

Homo sapiens

Homeobox-containing protein 1

PDB Structure

PDB	4J19
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	HOT1 is a mammalian direct telomere repeat-binding protein contributing to telomerase recruitment. Kappei, D., Butter, F., Benda, C., Scheibe, M., Draskovic, I., Stevense, M., Novo, C.L., Basquin, C., Araki, M., Araki, K., Krastev, D.B., Kittler, R., Jessberger, R., Londono-Vallejo, J.A., Mann, M., Buchholz, F. Embo J.