CATH Classification
Domain Context
CATH Clusters
| Superfamily | 2.40.50.100 |
| Functional Family | DNA-directed RNA polymerase subunit beta |
Enzyme Information
| 2.7.7.6 |
DNA-directed RNA polymerase.
based on mapping to UniProt P0A8T7
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).
-!- Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. -!- Can initiate a chain de novo. -!- In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized. -!- See also EC 2.7.7.19 and EC 2.7.7.48.
|
UniProtKB Entries (1)
| P0A8T7 |
RPOC_ECOLI
Escherichia coli K-12
DNA-directed RNA polymerase subunit beta'
|
PDB Structure
| PDB | 4IQZ |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
The crystal structure of a large insert in RNA polymerase (RpoC) subunit from E. coli
To be Published
|