CATH Domain 4ikcA00

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.90	Alpha-Beta Complex
	3.90.190	Protein-Tyrosine Phosphatase; Chain A
	3.90.190.10	Protein tyrosine phosphatase superfamily

Domain Context

CATH Clusters

Superfamily	Protein tyrosine phosphatase superfamily
Functional Family	phosphatidylinositol phosphatase PTPRQ isoform X1

Enzyme Information

3.1.3.48	Protein-tyrosine-phosphatase. based on mapping to UniProt Q9UMZ3 Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate. -!- Dephosphorylates O-phosphotyrosine groups in phosphoproteins, such as the products of EC 2.7.10.2.
3.1.3.-	Phosphoric monoester hydrolases. based on mapping to UniProt Q9UMZ3

UniProtKB Entries (1)

PTPRQ_HUMAN

Homo sapiens

Phosphatidylinositol phosphatase PTPRQ

PDB Structure

PDB	4IKC
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structural basis for the dephosphorylating activity of PTPRQ towards phosphatidylinositide substrates Yu, K.R., Kim, Y.J., Jung, S.K., Ku, B., Park, H., Cho, S.Y., Jung, H., Chung, S.J., Bae, K.H., Lee, S.C., Kim, B.Y., Erikson, R.L., Ryu, S.E., Kim, S.J. Acta Crystallogr.,Sect.D