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1 keywords

CATH Domain 4iczA00

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.90 Alpha-Beta Complex
Topology 3.90.190 Protein-Tyrosine Phosphatase; Chain A
Homologous Superfamily 3.90.190.10 Protein tyrosine phosphatase superfamily

Domain Context

CATH Clusters

Superfamily Protein tyrosine phosphatase superfamily
Functional Family tyrosine-protein phosphatase non-receptor type 9

Enzyme Information

3.1.3.48
Protein-tyrosine-phosphatase.
based on mapping to UniProt P43378
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.
-!- Dephosphorylates O-phosphotyrosine groups in phosphoproteins, such as the products of EC 2.7.10.2.

UniProtKB Entries (1)

P43378
PTN9_HUMAN
Homo sapiens
Tyrosine-protein phosphatase non-receptor type 9

PDB Structure

PDB 4ICZ
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
HER2 1221/1222 phosphorylation regulated by PTPN9
Xu, Y.F., Wang, H.M., Liu, C.H., Yu, X., Sun, J.P.
To be Published
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