CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.720 | Alkaline Phosphatase, subunit A |
|
3.40.720.10 | Alkaline Phosphatase, subunit A |
Domain Context
CATH Clusters
| Superfamily | Alkaline Phosphatase, subunit A |
| Functional Family | Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 |
Enzyme Information
| 3.1.4.1 |
Phosphodiesterase I.
based on mapping to UniProt P06802
Hydrolytically removes 5'-nucleotides successively from the 3'-hydroxy termini of 3'-hydroxy-terminated oligonucleotides.
-!- Hydrolyzes both ribonucleotides and deoxyribonucleotides. -!- Has low activity toward polynucleotides. -!- A 3'-phosphate terminus on the substrate inhibits hydrolysis.
|
| 3.6.1.9 |
Nucleotide diphosphatase.
based on mapping to UniProt P06802
A nucleoside triphosphate + H(2)O = a nucleotide + diphosphate.
-!- The enzyme preferentially hydrolyzes ATP, but can also hydrolyze other nucleoside 5' triphosphates such as GTP, CTP, TTP and UTP to their corresponding monophosphates. -!- In vitro the enzyme also acts as a nucleotidohydrolase on ADP, NAD(+), NADP(+), FAD, and CoA. -!- Formerly EC 3.6.1.19.
|
| 3.1.4.39 |
Alkylglycerophosphoethanolamine phosphodiesterase.
based on mapping to UniProt Q9R1E6
1-alkyl-sn-glycero-3-phosphoethanolamine + H(2)O = 1-alkyl-sn-glycerol 3-phosphate + ethanolamine.
-!- Also acts on acyl and choline analogs.
|
UniProtKB Entries (1)
| Q9R1E6 |
ENPP2_MOUSE
Mus musculus
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2
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PDB Structure
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| Organism | |
| Primary Citation |
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